Pakistan were 308 for a loss of eight wickets at the close of play on Wednesday, the second day of the first Test against South Africa at the National Stadium.
The home team is leading by 88 in reply to South Africa, who were all out for 220 in their first innings.
Pakistan's recovery was led by Fawad Alam (109), Faheem Ashraf (64) and Azhar Ali (51).
The two-match series marks South Africa's first trip to Pakistan in 14 years.
